the gateway to the majestic Big Horn Mountains. welcome to the Hampton Inn & Suites-Buffalo, WY. Nestled in the foothills of the Big Horn Mountains, halfway between Mount Rushmore and Yellowstone National Park, the area surrounding the Hampton Inn & Suites® Buffalo hotel is a destination in its own right. Our location in historic Buffalo, Wyoming, at the crossroads of Interstate 90, Interstate 25 and US Highway 16, boasts scenic creek-side and mountain views and offers the perfect place to uncover all that this stunning Big Horn Mountain region has to offer. Whether you're here for business or pleasure, you'll want to explore this beautiful area. Discover its lush grasslands, rolling hills and steep valleys. Go boating on crystal-clear Lake DeSmet, just north of town. Head to Cloud Peak Wilderness Area for a day hike. Do some mountain biking along Clear Creek. Take in the scenery along Cloud Peak Scenic Byway. And that's just the beginning! Historic downtown Buffalo, just two miles away, boasts a main street with more than a dozen historic buildings and museums. We're also two miles from Washington Memorial Park Swimming Pool, the largest free outdoor swimming pool in the region. Discover the Hampton Inn & Suites Buffalo, WY hotel, the gateway to the majestic Big Horn Mountains. services & amenities Even if you're in Buffalo to enjoy the great outdoors, we want you to enjoy our great indoors as well. That's why we offer a full range of services and amenities at our hotel to make your stay with us exceptional. Are you planning a meeting? Wedding? Family reunion? Little League game? Let us help you with our easy booking and rooming list management tools. * Meetings & Events * Local Restaurant Guide.