Welcome to East Syracuse, New York Our hotel's location in Dewitt provides unbeatable convenience. Because we're situated off Interstate 481 from exit 3W in East Syracuse, we close to attractions and businesses. When you stay with us, you're making the smart choice. We offer the name you trust with the service you deserve at the price that fits your budget. Our New York hotel is near Sensis, Lasik Provision, Kemper, Bristol-Myers Squibb, Blue Cross Blue Shield and Prudential, right in the middle of all the action. But our central location isn't the only thing we offer; we also boast a well-appointed 24-hour business center, which features a fax, printer and free high-speed, wireless Internet access. Experience the best of Salt City attractions like the Rosamond Gifford Zoo, Alliance Bank Stadium and Milton J. Rubenstein Museum of Science. You can revel in the Syracuse skyline from Onondaga Lake Park, cheer on the Orange at the Carrier Dome and tour the Salt Museum during your stay in East Syracuse, New York. Other hotels cannot match the outstanding service you'll experience at the Holiday Inn Express® East Syracuse . Here, you can enjoy a swim in our heated, indoor pool or recharge at the state-of-the-art fitness center while you watch your favorite program on a flat screen TV. Stay your way all day long with a complimentary breakfast every morning and a practical, yet comfortable room to retire to in the evening. Book today!